Hormones travel through the bloodstream and interact with the gut because gut cells have hormone receptors. Oestrogen, progesterone, thyroid hormones, insulin, and cortisol all signal to the gut to help control digestion, nutrient absorption, gut movement, and the balance of bacteria. Gut bacteria also help break down, recycle, and remove hormones, keeping levels healthy and preventing overload.
Disruption in this system can affect a wide range of conditions. Hormonal shifts or gut imbalance can influence blood sugar control, linking gut health to diabetes and metabolic syndrome. Autoimmune conditions, including thyroid disorders and arthritis, are influenced by gut–hormone interactions, as are food intolerances and sensitivities. Stress, trauma, or PTSD can raise cortisol, which disrupts gut bacteria and digestion, while poor gut health can amplify hormone-related symptoms like fatigue, mood changes, irregular cycles, bloating, and low libido.
Supporting gut health with a nutrient-rich diet, hydration, and healthy lifestyle choices helps hormones and gut bacteria work together, protecting digestion, immune function, and overall wellbeing.